P.E.A.R.L. Advanced Cell Signaling System

Regenerative Aesthetics Breakthrough Now Available at Rejuvience Med Spa Scottsdale

Rejuvience Med Spa is among the first regenerative aesthetics practices in Scottsdale to offer P.E.A.R.L. by AnteAGE, the revolutionary post-treatment topical that combines exosomes and PDRN in one powerful system.

This innovative treatment redefines what’s possible in skin rejuvenation, delivering transformative results when paired with advanced aesthetic procedures like Procell Microchanneling and Tixel Skin Resurfacing.

An image of AnteAGE P.E.A.R.L. vials at Rejuvience Med Spa in Scottsdale, Arizona

What is P.E.A.R.L.?

P.E.A.R.L. Advanced Cell Signaling System represents a paradigm shift in regenerative skincare. It improves cell-to-cell communication, reminding your skin how to behave like its younger self.


Its delivery system improves bioavailability to improve collagen production for skin volume while improving your skin barrier’s texture and strength for visibly smoother, more resilient, radiant-looking skin.

As the first treatment of its kind, P.E.A.R.L. synergistically combines:

  • P – PDRN  A Salmon DNA derivative that boosts tissue regeneration and DNA repair, improving elasticity and hydration
  • E – Exosomes  Accelerates healing and cell regeneration and stimulates collagen and elastin production
  • A – Antioxidants Brightens, evens tone and protects against UV damage and environmental stressors
  • R – Recombinant Growth Factors  A bio-signal cocktail that firms and brightens
  • L – L-Amino Acids Essential nutrients that the body cannot synthesize on its own needed for tissue repair 

Available with Procell Microchanneling and Tixel Skin Resurfacing treatments.

The Science Behind P.E.A.R.L.

Developed by AnteAGE’s leading experts in exosome and biosome technology, P.E.A.R.L. works at the cellular level to restore your skin’s youthful function.

Here’s how:

  • Enhanced Cell Communication Exosomes act as intelligent messengers, teaching skin cells to behave like their younger selves by delivering targeted repair signals.
  • DNA Repair & Collagen Stimulation PDRN activates fibroblasts (your skin’s collagen-producing cells) while providing the molecular building blocks needed for DNA synthesis and tissue regeneration.
  • Increased Bioavailability The P.E.A.R.L. formulation dramatically improves ingredient absorption, ensuring maximum penetration and effectiveness.
  • Accelerated Healing The combination reduces inflammation, speeds recovery time, and optimizes the healing response after aesthetic treatments.
 

Together, these mechanisms reignite collagen production, improve skin texture and tone, strengthen your protective skin barrier, and reveal visibly smoother, more resilient, radiant skin.

What Can P.E.A.R.L. Treat?

P.E.A.R.L. paired with professional skin rejuvenation treatments at Rejuvience Med Spa addresses multiple skin concerns:

  • Fine lines and wrinkles
  • Loss of skin firmness and elasticity
  • Uneven skin tone and texture
  • Enlarged pores
  • Acne scars and other scarring
  • Sun damage and photodamage
  • Dull, lackluster complexion
  • Skin barrier dysfunction
  • Overall skin aging and degradation

 

This treatment is suitable for all skin types and can be customized to your specific concerns and aesthetic goals.

Frequently Asked Questions

How many treatments will I need?

Most see significant improvement after a single treatment, though a series of 3-4 sessions spaced 4-6 weeks apart may be recommended for optimal results depending on your concerns.

Is there downtime?

Mild redness and sensitivity typically resolve within 24-48 hours. You can wear makeup and resume most activities the next day.

How soon will I see results?

New collagen and elastin that begin forming after treatment typically become visible by the end of week 2 beginning of week 3 post-treatment, sometimes sooner. While collagen does continue to enhance for another 3 to 6 months, by the end of week 4 post-treatment, you’ll see most of the visible results. 

Is P.E.A.R.L. safe?

Yes. P.E.A.R.L. is manufactured in AnteAGE’s FDA registered California headquarters following academic best practices and International Society for Extracellular Vesicles (ISEV) guidelines, ensuring the highest quality and safety standards.

Why Trust Rejuvience Med Spa Scottsdale

EXPERIENCE THE REJUVIENCE DIFFERENCE

At Rejuvience Med Spa, delivering great results with advanced technology that helps improve your skin’s health is our highest priority. When choosing a med spa in Scottsdale for advanced anti-aging treatments, credentials and expertise matter. Here’s why busy professionals throughout the Valley whose image is their brand trust us with their appearance:

LICENSED MEDICAL PROFESSIONALS

Our med spa is fully licensed in Arizona and staffed by licensed professionals with specialized training in advanced regenerative treatments. We adhere to the highest standards of safety, hygiene, and professional care.

REGENERATIVE AESTHETICS SPECIALISTS

As a regenerative aesthetics practice, we apply best-in-class skin rejuvenation technologies and the most advanced medical-grade bioactives to improve skin barrier health, enhance cellular function, and deliver noticeable results. Our treatments are designed to work with your body’s natural processes, not against them.

CUTTING-EDGE TECHNOLOGIES

We invest in proven, FDA-cleared technologies with tolerable treatments that deliver superior results. For example, our Age Repair Trifecta combines three award-winning technologies in a single treatment protocol designed for busy professionals with aging skin who need real results without days or even weeks of downtime. 

AUTHENTIC PRODUCTS

We use only genuine, medical-grade products sourced directly from USA-based manufacturers for our in-clinic treatments. All of our treatments feature premium-quality ingredients and bioactives that are clinically proven to enhance skin health and appearance.

PERSONALIZED APPROACH

We understand that every person has unique skin concerns and aesthetic goals. Before recommending any treatment, we conduct a thorough consultation to assess your specific needs. We can and do create customized combined-technology treatments to achieve optimal results for your goals.

COMMITMENT TO EDUCATION

Our team stays at the forefront of advances in regenerative aesthetics through ongoing research, education, and training. We’re passionate about sharing our knowledge, ensuring you understand the science behind your treatments and how to best maintain results.

TRANSPARENCY AND INTEGRITY

We believe in setting realistic expectations and providing transparent information about treatment options, expected results, and pricing. We’ll never recommend unnecessary treatments or pressure you into decisions that aren’t right for you. We do refer to a dermatologist or other specialized practitioner when we think it’s appropriate. 

THE SCOTTSDALE STANDARD OF EXCELLENCE

Located in the heart of Scottsdale, Rejuvience Med Spa embodies the premium quality and exceptional service that the area is known for. We’re proud to be part of this community and to serve the those who call it home.

COMPLIMENTARY CONSULTATIONS

Great looking skin is healthy skin, and there have never been so many treatment and production to choose from.  

To help you better understand the options for achieving your goals, we provide a complimentary consultation. During your appointment we’ll discuss your concerns and available treatments in the medical aesthetics industry. 

We understand we are not the right fit for everyone, and we do refer out when we think a different specialist will be of more help.  

There’s no cost, and there’s no obligation.